Xanthan gum-based fluid thickener decreases postprandial blood glucose associated with increase of Glp1 and Glp1r expression in ileum and alteration of gut microbiome

Yuki Nagasawa,Sayaka Katagiri,Kazuharu Nakagawa,Tomomitsu Hirota,Kanako Yoshimi,Aritoshi Uchida,Masahiro Hatasa,Keiji Komatsu,Takahiko Shiba,Yujin Ohsugi, Naofumi Uesaka,Takanori Iwata,Haruka Tohara

Journal of Functional Foods（2022）

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摘要

•Xanthan gum-based fluid thickener suppressed postprandial blood glucose levels.•Xanthan gum-based fluid thickener upregulated Glp1 and Glp1r expression in the ileum.•Erysipelotrichales showed a positive correlation with Glp1 and Glp1r expression.•Christensenellaceae showed positive correlation with Glp1 and Glp1r expression.

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关键词

Nutrients,Xanthan gum,Fluid thickener,Postprandial blood glucose,Gut microbiome

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