Fiscal consequences of Alzheimer's disease and informal care provision in the UK: A “government perspective” microsimulation

•Alzheimer’s disease (AD) has a substantial impact on the UK government finances.•The fiscal loss to the UK government is £73,749 per person and carer affected by AD.•Welfare support and payments account for 60% of the estimated fiscal loss due to AD.•Lost earnings for informal carers are estimated at £27,189 over the AD continuum.•Total fiscal consequences of diseases should inform health policy decision-making.