Plasma concentrations of levobupivacaine in neonates during caudal epidural analgesia maintained over 48 hours.

Jan Sipek,Pavla Pokorna,Martin Sima,Ivan Berka,Tomas Hlozek, Jitka Styblova,Vladimir Mixa,Barbora Nedomova

Bratislavske lekarske listy（2023）

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摘要

Caudal epidural analgesia with levobupivacaine lasting longer than 48 hours appears to be safe providing that free levobupivacaine levels are below the presumed threshold for toxicity (Tab. 1, Fig. 1, Ref. 29). Text in PDF www.elis.sk Keywords: free levobupivacaine, total levobupivacaine, neonate, caudal continuous epidural analgesia, postoperative pain.

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free levobupivacaine,total levobupivacaine,neonate,caudal continuous epidural analgesia,postoperative pain

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