Separation and characterization of the polymerized impurities in oxacillin sodium by 2D HPSEC and HPLC IT-TOF MS.

Jiarui Gao,Fan Wang,Xiangyu Zhang,Bingqi Zhu, Xin Chen,Ping Li,Ping Zhou,Jinqi Zheng,Jian Wang

Rapid communications in mass spectrometry : RCM（2023）

引用 1|浏览6

暂无评分

摘要

The mechanisms of the formation of degradation impurities in oxacillin sodium were studied. The newly established RP-HPLC methods could effectively separate and detect polymerized impurities and unknown impurities in oxacillin sodium. The study of the impurity profile in oxacillin sodium provided a scientific basis for the improvement of official monographs in pharmacopoeias.

查看译文

关键词

oxacillin sodium,polymerized impurities,2d hpsec,hplc

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要