Therapeutic Drug Monitoring of Lacosamide: Is 10 to 20 mg/L a Suitable Reference Range for Patients With Epilepsy?

Sara Otero Torres, Roser Juvany Roig,Mercè Falip Centellas, Miriam Casellas Gibert, Mónica Estopiñá Antolí,Raül Rigo Bonnin,Jacint Xavier Sala-Padro, Ramón Jódar Massanés

Clinical neuropharmacology（2023）

引用 0|浏览1

暂无评分

摘要

The 10 to 20 mg/L reference range clearly increases toxicity in patients treated with LCM. Adjusting the reference range upper limit to 12 mg/L with a routine therapeutic drug monitoring program is suggested, to achieve a reasonable probability of efficacy and decrease toxicity.

查看译文

关键词

lacosamide,reference range,therapeutic drug monitoring,side effects,tolerability

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要