The Post-insertion Method for the Preparation of PEGylated Liposomes

PEGylation is a crucial process for decorating the surface of liposomes with polyethylene glycol (PEG) for clinical use. This process endows the liposomes extended circulation time and improved stability in vivo. The post -insertion method is one of the well -established techniques for PEGylation. This method requires only one-step incubation to accomplish the transfer of PEGylated lipids from PEGylated lipid -based micelles into the membranes of preformed liposomes.