Is High-Dose Tranexamic Safe in Spine Surgery? A Systematic Review and Meta-Analysis.

Izzet Akosman,Francis Lovecchio,Mitchell Fourman,Manuel Sarmiento,Keith Lyons,Stavros Memtsoudis,Han Jo Kim

Global spine journal（2023）

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摘要

Compared to LD TXA or placebo, there is moderate evidence that HD is not associated with an increased risk of medical complications. Compared to LD, there is moderate evidence that HD reduces transfusion requirements. High-Dose TXA can be safely utilized in healthy patients undergoing major spine surgery.

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关键词

complications,dosing,high dose,low dose,spine,tranexamic acid

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