Humoral SARS-CoV-2 immunogenicity wanes 3 months after heterologous inactivated vaccine followed by ChAdOx1 nCoV-19 in autoimmune rheumatic diseases.

Parichat Uea-Areewongsa,Nawamin Pinpathomrat,Jomkwan Ongarj,Ratchanon Sophonmanee,Purilap Seepathomnarong,Bunya Seeyankem,Smonrapat Surasombatpattana,Porntip Intapiboon

Asian Pacific journal of allergy and immunology（2023）

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摘要

Our findings included changes to anti-RBD IgG levels and may inform vaccination strategies. SAR-CoV2 vaccine-induced immunity was lower in patients with ARDs than in HCs and decreased within 3 months, suggesting a need for booster vaccinations.

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