EPOXID HYDROLASE SINGLE GENE POLYMORPHISM (RS1051740) AND SEVERITY OF CHRONIC OBSTRUCTIVE DISEASE.

Inna Antonova,Oleksiy Gridnyev, Valentina Galchinskaya

Wiadomosci lekarskie (Warsaw, Poland : 1960)（2022）

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摘要

Conclusions: Patients with COPD and coronary heart disease who were carriers of a homozygous variant СС of the EPHX1 gene have a reliable association with a more severe course of COPD with frequent exacerbations (higher class according to GOLD classification and more severe symptoms of COPD according to the СAT questionnaire).

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关键词

EPHX1 , chronic obstructive pulmonary disease, coronary heart disease, epoxide hydrolase, exacerbations of chronic obstructive pulmonary disease, microsomal epoxide hydrolase

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