Infiltration of LPAR5 + macrophages in osteosarcoma tumor microenvironment predicts better outcomes.

Yi He,Haiting Zhou,Xiaojian Huang,Yunkun Qu,Yingguang Wang,Wenbin Pei,Rui Zhang,Sheng Chen,Hongbo You

Frontiers in immunology（2022）

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摘要

We identified a TME-related gene, LPAR5, which is a promising indicator for TME remodeling in osteosarcoma. Particularly, LPAR5 macrophages might have great potential to be a prognostic factor and therapeutic target for osteosarcoma.

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关键词

CIBERSORT,LPAR5,estimate,macrophage,osteosarcoma,tumor microenvironment

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