Association of QT interval-prolonging drugs with clinical trial eligibility in patients with advanced cancer.

Elizabeth J Rowe,Tyler Shugg,Reynold C Ly,Santosh Philips,Marc B Rosenman,John T Callaghan,Milan Radovich,Brian R Overholser,Bryan P Schneider,James E Tisdale,Todd C Skaar

Frontiers in cardiovascular medicine（2022）

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摘要

This study demonstrates that prescriptions for QT-prolonging drugs were associated with longer QTc measurements and increased odds of being excluded from cancer clinical trials.

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关键词

QT interval,QT-prolonging drugs,QTc,cancer,clinical trial eligibility,clinical trial exclusion

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