Faecal metabolite deficit, gut inflammation and diet in Parkinson's disease: Integrative analysis indicates inflammatory response syndrome.

Aisha Augustin,Adrien Le Guennec,Chianna Umamahesan, Aidan Kendler-Rhodes,Rosalind M Tucker,Elena Chekmeneva,Panteleimon Takis,Matthew Lewis, Karthik Balasubramanian, Neville DeSouza,Benjamin H Mullish,David Taylor,Suzanne Ryan,Kevin Whelan,Yun Ma,Mohammad A A Ibrahim,Ingvar Bjarnason,Bu' Hussain Hayee,André Charlett,Sylvia M Dobbs,R John Dobbs,Clive Weller

Clinical and translational medicine（2023）

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摘要

Emerging picture is of (i) clinical phenotype being described by deficits in microbial metabolites essential to gut health; (ii) intestinal inflammation; (iii) a systemic inflammatory response syndrome.

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关键词

Parkinson's disease,faecal metabolome,intestinal inflammation,systemic immunome

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