Fatty acid composition and metabolic partitioning of α-linolenic acid are contingent on life stage in human CD3 + T lymphocytes.

Annette L West,Johanna von Gerichten,Nicola A Irvine,Elizabeth A Miles,Karen A Lillycrop,Philip C Calder,Barbara A Fielding,Graham C Burdge

Frontiers in immunology（2022）

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摘要

Together these findings show that fatty acid metabolism in human T lymphocytes changes across the life course in a manner that may facilitate the adaptation of immune function to different life stages.

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关键词

CD69,T lymphocyte,essential fatty acid,fatty acid (composition),hydroxyoctadecadienoic acids,life course,lipid droplet,α-linolenic acid

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