MYCBP2 expression correlated with inflammatory cell infiltration and prognosis immunotherapy in thyroid cancer patients.

Guilin Wang,Chen Miao,Lijun Mo,Ulf D Kahlert,Jinfeng Wu,Minglin Ou,Renxiang Huang,Ruifa Feng,Weiyi Pang,Wenjie Shi

Frontiers in immunology（2022）

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摘要

In this study, we found that MYCBP2 may be a predictive biomarker for ICI efficacy in TC patients. High MYCBP2 expression was associated with significantly enriched immune cell infiltration. MYCBP2 may also be involved in the regulation of signaling pathways associated with anti-tumor immune responses or the production of inflammatory factors.

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关键词

MYCBP2,immune checkpoint inhibitors,myc binding protein 2,prognosis,thyroid cancer

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