The Calcineurin-Drp1-Mediated Mitochondrial Fragmentation Is Aligned with the Differentiation of c-Kit Cardiac Progenitor Cells.

Attaur Rahman,Yuhao Li,Nur Izzah Ismail,To-Kiu Chan,Yuzhen Li,Dachun Xu,Hao Zhou,Sang-Bing Ong

International journal of stem cells（2022）

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摘要

The findings from this study provide an alternative view of the role of mitochondrial fusion-fission in the differentiation of cardiac progenitor cells and the potential of pharmacologically manipulating the mitochondria to direct progenitor cell fate.

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关键词

Calcineurin,Cardiac progenitor cells,Drp1,Mitochondrial fragmentation,Stem cell differentiation,c-kit

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