Vernonia amygdalina Delile Induces Apoptotic Effects of PC3 Cells: Implication in the Prevention of Prostate Cancer.

Clement G Yedjou,William Johnson, Solange S Tchounwou,Shaloam Dasari,Sylvianne Njiki,Paul B Tchounwou

Journal of biomedical research & environmental sciences（2022）

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摘要

These results suggest that inhibition of cancer cell growth, induction of cell cycle arrest, and apoptosis through caspase-3 activation and nucleosomal DNA fragmentation are involved in the therapeutic mechanisms of VAD as a candidate drug towards the prevention and/or treatment of PCa.

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关键词

DNA fragmentation,Vernonia amygdalina Delile,apoptosis,cell cycle arrest,prostate cancer

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