Structure and function of aldopentose catabolism enzymes involved in oxidative non-phosphorylative pathways
Biotechnology for biofuels and bioproducts(2022)
摘要
Platform chemicals and polymer precursors can be produced via enzymatic pathways starting from lignocellulosic waste materials. The hemicellulose fraction of lignocellulose contains aldopentose sugars, such as d -xylose and l -arabinose, which can be enzymatically converted into various biobased products by microbial non-phosphorylated oxidative pathways. The Weimberg and Dahms pathways convert pentose sugars into α-ketoglutarate, or pyruvate and glycolaldehyde, respectively, which then serve as precursors for further conversion into a wide range of industrial products. In this review, we summarize the known three-dimensional structures of the enzymes involved in oxidative non-phosphorylative pathways of pentose catabolism. Key structural features and reaction mechanisms of a diverse set of enzymes responsible for the catalytic steps in the reactions are analysed and discussed.
更多查看译文
关键词
Aldopentose,Non-phosphorylative pathways,Pentose catabolism,Aldose-1-dehydrogenase,Lactonase,Sugar acid dehydratase,Ketoglutarate-semialdehyde dehydrogenase,Aldolase
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要