Wall shear stress-related plaque growth of lipid-rich plaques in human coronary arteries: an near-infrared spectroscopy and optical coherence tomography study.

Eline M J Hartman,Giuseppe De Nisco,Annette M Kok,Mariusz Tomaniak,Fay M A Nous,Suze-Anne Korteland,Frank J H Gijsen,Wijnand K den Dekker,Roberto Diletti,Nicolas M D A van Mieghem,Jeroen M Wilschut,Felix Zijlstra,Anton F W van der Steen,Ricardo P J Budde,Joost Daemen,Jolanda J Wentzel

Cardiovascular research（2022）

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摘要

This study demonstrates that NIRS- and OCT-detected lipid-rich regions exposed to low WSS are subject to enhanced plaque growth over a 1-year follow-up. The presence of lipids and low WSS proves to have a synergistic effect on plaque growth.

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关键词

Coronary artery disease,Intravascular ultrasound,Near-infrared spectroscopy,Optical coherence tomography,Wall shear stress

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