Using Serum Specimens for Real-Time PCR-Based Diagnosis of Human Granulocytic Anaplasmosis, Canada.

Carl Boodman, Courtney Loomer,Antonia Dibernardo,Todd Hatchette,Jason J LeBlanc, Brooks Waitt,L Robbin Lindsay

Emerging infectious diseases（2023）

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摘要

Whole blood is the optimal specimen for anaplasmosis diagnosis but might not be available in all cases. We PCR tested serum samples collected in Canada for Anaplasma serology and found 84.8%-95.8% sensitivity and 2.8 average cycle threshold elevation. Serum can be acceptable for detecting Anaplasma spp. when whole blood is unavailable.

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关键词

Anaplasma phagocytophilum,Canada,PCR,anaplasmosis,bacteria,diagnostics,emerging infections,ticks,vector-borne infections,zoonoses

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