Integrative transcriptomic analysis in human and mouse model of anaphylaxis identifies gene signatures associated with cell movement, migration and neuroinflammatory signalling.

Frontiers in immunology(2022)

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摘要
Our study highlights the matched and extensive blood transcriptomic changes and suggests the involvement of discrete cellular components and upregulation of migration and neuroinflammatory pathways during anaphylaxis.
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关键词
anaphylaxis,basophils,cell movement,lipid activating nuclear receptors signaling,migration,neuroinflammatory signaling,neutrophils,transcriptome analysis
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