Fibrosis resolution in the mouse liver: Role of Mmp12 and potential role of calpain 1/2

Matrix Biology Plus(2023)

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摘要
•Fibrosis resolution involves more than collagen remodeling.•MMP-12-mediated elastin degration is key to fibrosis resolution.•Several ECM proteins actively turning over during late resolution.•Potential new role of calpains in fibrosis resolution.
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关键词
CCl4,ECM,ELISA,GO,LC-MS/MS,MMP,MPM,rtPCR,SDS
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