Melatonin for prevention of acute kidney injury in patients treated with intravenous polymyxin B: a double-blind, placebo-controlled randomised clinical trial.

Maria Helena Rigatto, Pedro Bergo, Giulia Baldissera,Eduarda Beck, Leonardo David, Lucas Santoro,Andressa Barros,Rafael Zanin, João Ismael Budelon Gonçalves,Diego Falci,Wolnei Caumo,Alexandre P Zavascki

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases(2022)

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摘要
Melatonin initiated in the first 48 hours of therapy did not reduce the incidence of AKI in patients treated with polymyxin B.
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关键词
Acute Kidney Injury,Melatonin,Mortality,Nephrotoxicity,Polymyxins
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