Pathogenesis of bronchopulmonary dysplasia in preterm neonates revealed by an RNA sequencing interaction network analysis.

Fengdan Xu,Yabo Mei,Yaozhong Zhang,Qin Chen,Jinfeng Liao,Xiaoguang He,Zhichun Feng,Xingyun Wang,Ning Li

Translational pediatrics（2022）

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摘要

This study identified 1 key upregulated lncRNA (i.e., ) in preterm neonatal BPD, and revealed the mechanism in preterm neonatal BPD from the lncRNA-miRNA-mRNA network. This key lncRNA gene could serve as a promising diagnostic biomarker for prenatal examinations.

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关键词

hsa-miR-6833-5p,MERGE.57185.1,Preterm neonatal bronchopulmonary dysplasia (preterm neonatal BPD),RNA sequencing (RNA-seq),eukaryotic translation initiation factor 5A (EIF5A)

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