A low prostate specific antigen predicts a worse outcome in high but not in low/intermediate-grade prostate cancer

Christian D. Fankhauser,Matthew G. Parry,Adnan Ali,Thomas E. Cowling,Julie Nossiter, Arun Sujenthiran,Brendan Berry,Melanie Morris,Ajay Aggarwal,Heather Payne,Jan van der Meulen,Noel W. Clarke

European Journal of Cancer（2023）

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摘要

•Large dataset describing the prognostic value of prostate-specific antigen (PSA) in localised prostate cancer.•In high-grade prostate cancer, a low or high PSA predicts poor outcomes.•In low/intermediate-grade prostate cancer, the higher the PSA the worse the outcome.•This confirms a more aggressive biology in low PSA secreting high-grade PCa.

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关键词

Prostate cancer,Prostatectomy,Radiotherapy,Brachytherapy,Androgen deprivation therapy,Prostate-specific antigen

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