Lactoferrin enhances neurite outgrowth via TrkA receptor in PC12 cells.

Mizukami Noa,Daichi Nagashima,Megumi Furukawa,Masahiro Toho,Takeaki Nitto,Kohsuke Hayamizu,Nobuo Izumo

Proceedings for Annual Meeting of The Japanese Pharmacological Society（2022）

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摘要

Lactoferrin (LF) is a multifunctional protein which have the antibacterial and immunomodulatory action in the milk of mammals. Recent studies have been investigated the effect of improvement of cognitive impairment in the central nerve system. However, the mechanisms underlying the effects of LF on neuron have not yet been elucidated. The aim of present study investigated the efficacy of LF on the cell outgrowth effect using by PC12 cells, and demonstrated to mechanisms of LF.

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lactoferrin,trka receptor,neurite outgrowth,pc12 cells

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