Long Non-Coding RNA CRNDE Functions as a Tumor Promoter by Modulating the ERK/MAPK Signaling Pathway in Neuroblastoma Cells.

Ting Zhang,Ming-Cui Fu,Wei-Qiang Tan,Hong-Liang Xia,Shu Dai,Qian-Wei Xiong,Yun Zhou,Zhi-Heng Li,Yi Wu,Xu Cao,Xiang-Ming Yan

Annals of clinical and laboratory science（2022）

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摘要

The present study revealed that CRNDE plays a critical role in the proliferation, apoptosis, migration, and invasion of neuroblastoma by altering the ERK/MAPK signaling pathway, representing a novel molecular target for the treatment of neuroblastoma.

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关键词

CRNDE,long non-coding RNA,neuroblastoma

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