Randomized active-controlled study of a single preoperative administration of duloxetine to treat postoperative pain and numbness after posterior lumbar interbody fusion surgery.

Tadanao Hiroki,Nao Fujita,Takashi Suto,Hideo Suzuki, Noboru Tsukamoto,Jo Ohta,Shigeru Saito,Hideaki Obata

Medicine（2022）

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摘要

A single preoperative 40-mg dose of duloxetine did not improve postoperative pain after PLIF, but did improve lower limb numbness. Duloxetine may suppress neuropathic pain-like symptoms after PLIF surgery.

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关键词

duloxetine,postoperative pain,single preoperative administration,numbness,active-controlled

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