Comparing Prospective Incident Severe Acute Respiratory Syndrome Coronavirus 2 Infection Rates During Successive Waves of Delta and Omicron in Johannesburg, South Africa.

Simiso Sokhela,Bronwyn Bosch,Andrew Hill,Bryony Simmons,Joana Woods,Hilary Johnstone,Shabir Madhi,Ambar Qavi,Leah Ellis,Godspower Akpomiemie, Esther Bhaskar,Jacob Levi,Jonathan Falconer,Manya Mirchandani,Carmen Perez Casas, Karlien Moller,Victoria Pilkington,Toby Pepperrell,Willem Daniel Francois Venter

Open forum infectious diseases（2022）

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摘要

In high-risk individuals in Johannesburg, during the Delta coronavirus disease 2019 wave, 22% (125/561) were positive, with 33% symptomatic (2 hospitalizations; 1 death). During Omicron, 56% (232/411) were infected, with 24% symptomatic (no hospitalizations or deaths). The remarkable speed of infection of Omicron over Delta poses challenges to conventional severe acute respiratory syndrome coronavirus 2 control measures.

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COVID-19,Delta,Omicron,SARS-CoV-2,South Africa

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