Modification of PLAC8 by UFM1 affects tumorous proliferation and immune response by impacting PD-L1 levels in triple-negative breast cancer.

Journal for immunotherapy of cancer(2022)

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摘要
Our current study discoveries a new PLAC8-regulated network in triple-negative breast cancer and provides corresponding guidance for the clinical diagnosis and immunotherapy of triple-negative breast cancer.
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关键词
Immunotherapy,PD-L1,PLAC8,Triple-negative breast cancer,UFMylation
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