Elevated inflammatory fecal immune factors in men who have sex with men with HIV associate with microbiome composition and gut barrier function.

Katherine M Littlefield,Jennifer M Schneider,Charles P Neff,Victoria Soesanto,Janet C Siebert,Nichole M Nusbacher,Nancy Moreno-Huizar,Ian M Cartwright,Abigail J S Armstrong,Sean P Colgen,Catherine A Lozupone,Brent E Palmer

Frontiers in immunology（2022）

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摘要

Taken together, these data demonstrate that inflammatory sIFs are elevated in MSM, regardless of HIV infection status, and are associated with the gut microbiome and intestinal barrier function.

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关键词

cytokines,gut microbiome,human immunodeficiency virus (HIV),immune factors,inflammation,men who have sex with men (MSM)

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