Kaempferol attenuated diabetic nephropathy by reducing apoptosis and promoting autophagy through AMPK/mTOR pathways.

Hongqin Sheng,Duo Zhang,Jiaqi Zhang,Yanmei Zhang,Zhaoyu Lu,Wei Mao,Xusheng Liu,Lei Zhang

Frontiers in medicine（2022）

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摘要

In conclusion, KPF might have a protective effect on DN through reduced apoptosis and enhanced podocytes autophagy, which were correlated with regulating AMPK/mTOR pathways.

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关键词

AMPK/mTOR pathway,Kaempferol,apoptosis,autophagy,diabetic nephropathy

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