Digestion, absorption, and transport properties of soy-fermented douchi hypoglycemic peptides VY and SFLLR under simulated gastrointestinal digestion and Caco-2 cell monolayers

Songfeng Yu,Wenjun Wang,Tingting Bu,Runan Zhao,Ruihao Niu,Ling Liu,Jiaheng Li,Jianping Wu,Donghong Liu

Food Research International（2022）

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摘要

•Peptide VY was resistant, whereas SFLLR was susceptible to simulated gastrointestinal digestion.•Two new hypoglycemic peptides (SFLL and SFL) were formed from digestion of SFLLR.•Transport of peptide VY and SFL was mediated by both paracellular diffusion and PepT1 route.•Transport of SFLLR and SFLL was paracellular diffusion.

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关键词

Douchi,Hypoglycemic peptides,Gastrointestinal digestion,Absorption,Transepithelial transport,Caco-2 cell monolayers

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