Difluoromethyl-1,3,4-oxadiazoles Are Slow-Binding Substrate Analog Inhibitors of Histone Deacetylase 6 with Unprecedented Isotype Selectivity.
JOURNAL OF BIOLOGICAL CHEMISTRY（2023）
Key words
histone deacetylase,histone deacetylase inhibitor,histone deacetylase 6,inhibition mechanism,epigenetics,X-ray crystallography,difluoromethyl oxadiazole,zinc-binding group,mechanism-based inhibitor
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