Human beta-defensin 1 circulating level and gene polymorphism in non-segmental vitiligo Egyptian patients.

Azza Gaber Antar Farag,Mohamed Abd AlMoneam Shoeib,Azza Zagloul Labeeb, Asmaa Shaaban Sleem, Hagar Mahmoud AbdElkader Khallaf,Amany Salah Khalifa,Mustafa Elsayed Elshaib,Nada Farag Elnaidany, Hayam Mohamed Aboelnasr Hanout

Anais Brasileiros de Dermatologia（2023）

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摘要

DEFB1 gene polymorphism (GG genotype and G allele) may modulate vitiligo risk and contribute to vitiligo development in Egyptian populations. Decreased circulating HBD-1 levels might have an active role in vitiligo etiopathogenesis that could be mediated through its possible anti-inflammatory effects.

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关键词

Genes,Polymorphism, genetic,Vitiligo

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