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Poor association between dihydropyrimidine dehydrogenase (DPYD) genotype and fluoropyrimidine-induced toxicity in an Asian population.

Masashi Kanai,Takahisa Kawaguchi,Masahito Kotaka,Dai Manaka,Junichi Hasegawa,Akinori Takagane,Yoshinori Munemoto,Takeshi Kato,Tetsuya Eto,Tetsuo Touyama,Takanori Matsui,Katsunori Shinozaki,Shigemi Matsumoto,Tsunekazu Mizushima,Masaki Mori,Junichi Sakamoto,Atsushi Ohtsu,Takayuki Yoshino,Shigetoyo Saji,Fumihiko Matsuda

Cancer medicine（2022）

引用 4|浏览13
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摘要
These data suggested that the DPYD genotype registered in CPIC plays a minor role in FP-related toxicities in an Asian population.
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关键词
DPYD ,Asian population,fluoropyrimidine,genotyping,toxicity
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