States of quinolinic acid excess in urine: A systematic review of human studies.

Frontiers in nutrition(2022)

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摘要
Quinolinic acid has been implicated in the pathophysiology of multiple conditions. Its urinary accumulation appears to be a feature of acute physiological stress and several chronic diseases. The exact significance of these findings is still under investigation, and further studies are needed to reveal the subsequent implications of this accumulation.
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关键词
NAD+,NAD+ biosynthesis,inflammation,metabolism,quinolinate phosphoribosyl transferase (QPRT),quinolinic acid (QA),tryptophan,urine
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