Delineating the molecular landscape of different histopathological growth patterns in colorectal cancer liver metastases.

Frontiers in immunology（2022）

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摘要

We surmised that HGPs are observable morphological changes resulting from the regulation of molecular expressions, which is the combined effect of the heterogeneity and remodeling of primary tumors seeds and liver soils.

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RNA sequencing,colorectal cancer liver metastases,histopathological growth pattern,soil and seeds,tumor microenvironment

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