Causes of preterm birth: Genetic factors in preterm birth and preterm infant phenotypes.

The journal of obstetrics and gynaecology research(2023)

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摘要
Investigation of the human genome, epigenome, and transcriptome helps to identify molecular mechanisms linked with preterm delivery and premature newborn clinical appearance in early and late neonatal life and even predict developmental outcomes. Further studies are needed to fully understand the implications of genetic changes in preterm births. These data could be used to develop targeted interventions aimed at selecting the most effective individual treatment and rehabilitation plan.
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关键词
de novo variants,epi,genome,premature birth,preterm neonate,transcriptome
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