Scleral Remolding-Related Gene Expression After Scleral Collagen Cross-Linking Using Ultraviolet A and Riboflavin in Myopic Guinea Pig Model.

Yushan Xu,Lingbo Lai,Zhe Chen, Yuqian Jia,Dengxin Gao,Xiaotong Lv,Yanzheng Song,Mingshen Sun,Yu Li,Fengju Zhang

Current eye research（2023）

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摘要

SCXL using UVA and riboflavin could influence the expression of scleral remolding-related genes, including COL1A1, MMP2, TIMP2, and ACTA2, and thus contribute to improving collagen synthesis and reducing collagen degradation and might have an effect on slowing myopia progression.

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关键词

Cross-linking,Guinea pig,gene expression,myopia,scleral remodeling,ultraviolet A

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