Development and verification of new monoclonal orthopedia homeobox (OTP) specific antibodies for pulmonary carcinoid diagnostics.

Laura Moonen,Jules L Derks, Lisa M V Lap, Britney J C A Marijnissen,Lisa M Hillen,Michael A den Bakker,Jan H von der Thüsen,Robert-Jan van Suylen,Wim Timens, Maria Bintanel,Eugenia Kuteeva,Anne-Marie C Dingemans,Ernst-Jan M Speel

Translational lung cancer research（2022）

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摘要

New monoclonal OTP specific antibodies have been developed and verified on different automated immunohistochemical staining platforms. The OTP specific monoclonal antibodies showed excellent agreement with the often-used polyclonal antibody allowing application in routine diagnostics.

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关键词

Pulmonary carcinoids,monoclonal antibody (mAb),neuroendocrine,orthopedia homeobox (OTP),prognostic

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