Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos

Jun Ito,Mio Kageyama,Shunsuke Hara,Takuya Sato,Koumei Shirasuna,Hisataka Iwata

Mitochondrion（2023）

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摘要

•Mitochondrial DNA (mtDNA) copy number and telomere length (TL) correlates in blastocysts.•Paternal aging affects the mtDNA and TL in blastocysts.•Paternal aging affects the mtDNA in issues of offspring.

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关键词

Mouse embryos,Paternal aging,Mitochondrial DNA,Telomere length

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