Alveolar Biomarker Profiles in Subphenotypes of the Acute Respiratory Distress Syndrome.

Neha A Sathe,Eric D Morrell,Pavan K Bhatraju,Michael B Fessler,Renee D Stapleton,Mark M Wurfel,Carmen Mikacenic

Critical care medicine（2023）

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摘要

Hyperinflammatory and hypoinflammatory ARDS subphenotypes did not display significant differences in alveolar biologic profiles. Identifying ARDS subgroups using BALF measurements is a unique approach that complements information obtained from plasma, with potential to inform enrichment strategies in trials of lung-targeted therapies.

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关键词

acute respiratory distress syndrome,bronchoalveolar lavage fluid,phenotype,precision medicine

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