Dapansutrile ameliorated chondrocyte inflammation and osteoarthritis through suppression of MAPK signaling pathway.
Human & experimental toxicology（2022）
摘要
Our study suggested that dapansutrile effectively inhibited chondrocyte inflammation by suppressing MAPK signaling pathway in vitro, and ameliorated cartilage degeneration in vivo, indicating an anti-inflammatory effect in OA treatment.
更多查看译文
关键词
Interleukin-1β,Osteoarthritis,dapansutrile,matrix metalloproteinase,mitogen-activated protein kinase pathway
AI 理解论文
溯源树
样例
生成溯源树，研究论文发展脉络
Chat Paper
正在生成论文摘要