Patchouli alcohol inhibits GPBAR1-mediated cell proliferation, apoptosis, migration, and invasion in prostate cancer.

Translational andrology and urology（2022）

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摘要

GPBAR1 is a promising drug target of PA, and was shown to regulate the proliferation, apoptosis, migration, and invasion of PCa cells through GPBAR1/NF-κB inhibition.

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关键词

G protein-coupled bile acid receptor 1 (GPBAR1),Patchouli alcohol,nuclear factor kappa B (NF-κB),prostate cancer (PCa),tumorigenesis

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