A vasculogenic mimicry prognostic signature associated with immune signature in human gastric cancer.

Jie Wang,Wei Xia,Yujie Huang,Haoran Li,Yuchen Tang,Ye Li,Bin Yi,Zixiang Zhang,Jian Yang,Zhifei Cao,Jian Zhou

Frontiers in immunology（2022）

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摘要

A VM index and a nomogram were constructed and showed satisfactory predictive performance. In addition, VM was confirmed to be widely involved in immune infiltration, suggesting that VM could be a promising target in guiding immunotherapy. Taken together, we identified SERPINF1 and TFPI2 as immunologic and prognostic biomarkers related to VM in GC.

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关键词

SERPINF1,TFPI2,gastric cancer,immune infiltration,nomogram,vasculogenic mimicry

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