A near-infrared GPX4 fluorescent probe for non-small cell lung cancer imaging.

Qiao Hu,Wanjie Zhu,Jianjun Du,Saran Long,Wen Sun,Jiangli Fan,Xiaojun Peng

Chemical communications (Cambridge, England)（2023）

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摘要

Glutathione peroxidase 4 (GPX4) is overexpressed in non-small cell lung cancer (H1299) cells. In this work, a near-infrared fluorescent probe ENBO-ML210 was developed. and imaging results showed that ENBO-ML210 could target and visualize GPX4 in H1299 cells, exhibiting potential for the diagnosis of non-small lung cancer.

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关键词

gpx4 fluorescent probe,near-infrared,non-small

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