Aspects of autism spectrum disorder and correlation with neuroimaging findings in tuberous sclerosis complex

Özge Dedeoğlu,Miray Çetinkaya,Betül Emine Derinkuyu,Erhan Aksoy,Ülkühan Öztoprak,Çiğdem Genç Sel,Hatice Nursun Özcan,Ayşe Aksoy,Deniz Yüksel

Clinical Neurology and Neurosurgery（2023）

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摘要

•Specific areas on brain MRI may help understanding the development of ASD in TSC patients.•The mean of total tuber count was determined to be higher in TSC patients with ASD.•Tubers tend to settle in the prefrontal cortex in TSC patients with ASD.•Generalized epileptiform activities on EEG and the rate of drug resistant epilepsy were more common in TSC patients with ASD.

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关键词

Tuberosclerosis Complex Disease,Autism Spectrum Disorder,Magnetic Resonance Imaging

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