Genomic characterization of Plasmodium falciparum genes associated with anti-folate drug resistance and treatment outcomes in eastern India: A molecular surveillance study from 2008 to 2017.

Sabyasachi Das,Satyajit Tripathy, Ankita Das, Meenakshi Kumari Sharma, Ayan Nag,Amiya Kumar Hati,Somenath Roy

Frontiers in cellular and infection microbiology（2022）

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摘要

This successive spread of mutations with high in vitro sulfadoxine-pyrimethamine resistance confirmed the progressive increase in antifolate resistance even after an 8-year withdrawal of sulfadoxine-pyrimethamine.

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Plasmodium falciparum,antifolate resistance,in vitro pyrimethamine resistance,in vitro sulfadoxine resistance,pfdhfr mutation,pfdhps mutation

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