Management of Patients with Advanced Prostate Cancer. Part I: Intermediate-/High-risk and Locally Advanced Disease, Biochemical Relapse, and Side Effects of Hormonal Treatment: Report of the Advanced Prostate Cancer Consensus Conference 2022.

Silke Gillessen,Alberto Bossi,Ian D Davis,Johann de Bono,Karim Fizazi,Nicholas D James,Nicolas Mottet,Neal Shore,Eric Small,Mathew Smith,Christopher Sweeney,Bertrand Tombal,Emmanuel S Antonarakis,Ana M Aparicio,Andrew J Armstrong,Gerhardt Attard,Tomasz M Beer,Himisha Beltran,Anders Bjartell,Pierre Blanchard,Alberto Briganti,Rob G Bristow,Muhammad Bulbul,Orazio Caffo,Daniel Castellano,Elena Castro,Heather H Cheng,Kim N Chi,Simon Chowdhury,Caroline S Clarke,Noel Clarke,Gedske Daugaard,Maria De Santis,Ignacio Duran,Ros Eeles,Eleni Efstathiou,Jason Efstathiou,Onyeanunam Ngozi Ekeke,Christopher P Evans,Stefano Fanti,Felix Y Feng,Valerie Fonteyne,Nicola Fossati,Mark Frydenberg,Daniel George,Martin Gleave,Gwenaelle Gravis,Susan Halabi,Daniel Heinrich,Ken Herrmann,Celestia Higano,Michael S Hofman,Lisa G Horvath,Maha Hussain,Barbara Alicja Jereczek-Fossa,Robert Jones,Ravindran Kanesvaran,Pirkko-Liisa Kellokumpu-Lehtinen,Raja B Khauli,Laurence Klotz,Gero Kramer,Raya Leibowitz,Christopher J Logothetis,Brandon A Mahal,Fernando Maluf,Joaquin Mateo,David Matheson,Niven Mehra,Axel Merseburger,Alicia K Morgans,Michael J Morris,Hind Mrabti,Deborah Mukherji,Declan G Murphy,Vedang Murthy,Paul L Nguyen,William K Oh,Piet Ost,Joe M O'Sullivan,Anwar R Padhani,Carmel Pezaro,Darren M C Poon,Colin C Pritchard,Danny M Rabah,Dana Rathkopf,Robert E Reiter,Mark A Rubin,Charles J Ryan,Fred Saad,Juan Pablo Sade,Oliver A Sartor,Howard I Scher,Nima Sharifi,Iwona Skoneczna,Howard Soule,Daniel E Spratt,Sandy Srinivas,Cora N Sternberg,Thomas Steuber,Hiroyoshi Suzuki,Matthew R Sydes,Mary-Ellen Taplin,Derya Tilki,Levent Türkeri,Fabio Turco,Hiroji Uemura,Hirotsugu Uemura,Yüksel Ürün,Claire L Vale,Inge van Oort,Neha Vapiwala,Jochen Walz,Kosj Yamoah,Dingwei Ye,Evan Y Yu,Almudena Zapatero,Thomas Zilli,Aurelius Omlin

European urology(2023)

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摘要
The Advanced Prostate Cancer Consensus Conference (APCCC) provides a forum to discuss and debate current diagnostic and treatment options for patients with advanced prostate cancer. The conference aims to share the knowledge of international experts in prostate cancer with health care providers and patients worldwide. At each APCCC, a panel of physician experts vote in response to multiple-choice questions about their clinical opinions and approaches to managing advanced prostate cancer. This report presents voting results for the subset of questions pertaining to intermediate- and high-risk and locally advanced prostate cancer, biochemical relapse after definitive treatment, advanced (next-generation) imaging, and management of side effects caused by hormonal therapies. The results provide a practical guide to help clinicians and patients discuss treatment options as part of shared multidisciplinary decision-making. The findings may be especially useful when there is little or no high-level evidence to guide treatment decisions.
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关键词
Adjuvant therapy,Biochemical recurrence,Hormonal treatment,Locally advanced prostate cancer,Next-generation imaging,Prostate cancer,Prostate-specific membrane antigen positron emission tomography imaging,Salvage radiation therapy,Salvage therapy,Side effects
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