Neuroprotective effect of thyroid hormones on methamphetamine-induced neurotoxicity via cell surface receptors

Seyedeh Masoumeh Seyedhosseini Tamijani,Elmira Beirami,Saina Dargahi,Abolhassan Ahmadiani,Leila Dargahi

Neuroscience Letters（2023）

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摘要

•Methamphetamine (MA) reduced cell viability in primary hippocampal neurons culture.•Thyroid hormones (THs) treatment attenuated MA-induced neurotoxicity.•THs reduced MA neurotoxicity through the integrin αvβ3 cell surface receptors.•THs may represent a treatment for MA neurotoxicity.

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关键词

Methamphetamine,Thyroid hormones,Integrin αvβ3 receptors,Rat primary hippocampal neurons

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